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Download Goljan USMLE Step 1 Audio Lectures Free
Today we will share stuff related to Medical Audios. We will share Goljan Pathology Audio Lectures (Complete Lectures). Links to Download Audio Lectures are given bellow.
“1. Most imp: have to go into anaerobic glycolysis; end product is lactic acid (pyruvate is converted to lactate b/c of increased NADH); need to make NAD, so that the NAD can feedback into the glycolytic cycle to make 2 more ATP. Why do we have to use anaerobic glycolysis with tissue hypoxia? Mitochondria are the one that makes ATP; however, with anaerobic glycolysis, you make 2 ATP without going into the mitochondria. Every cell (including RBC’s) in the body is capable of
performing anaerobic glycolysis, therefore surviving on 2 ATP per glucose if you have tissue hypoxia. Mitochondrial system is totally shut down (no O2 at the end of the electron transport system – can only get 2 ATP with anaerobic glycolysis). Good news – get 2 ATP Bad news – build up of lactic acid in the cell and outside the cell (increased anion-gap metabolic acidosis with tissue hypoxia) due to lactic acidosis from anaerobic glycolysis. However, causes havoc inside the cell b/c increase of acid within a cell will denature proteins (with structural proteins messed up, the configuration will be altered); enzymes will be denatured, too. As a result, cells cannot autodigest anymore b/c enzymes are destroyed b/c buildup of acid. Tissue hypoxia will therefore lead to COAGULATION necrosis (aka infarction). Therefore, buildup of lactic acid within the cell will lead to Coagulation necrosis.
Apr 27, 2014 If nothing else, he helps you develop good instincts so you can 'play odds' better. If you can't get through all of his lectures, definitely do nutrition, heme/onc, and MSK/derm. The fact that Goljan audio is falling out of favor just makes it all the more valuable IMO. Nov 05, 2018 Goljan Pathology Lecture Notes (Typed Pathology Notes) PDF. GOLJAN PATHOLOGY LECTURE NOTES. GOLJAN PATHOLOGY LECTURE NOTES very important resource to prepare for USMLE step 1 2018,they will help you to master and review all of the pathology beside usmle step 1 lecture.
2. 2nd problem of lacking ATP: all ATP pumps are screwed up b/c they run on ATP. ATP is the power, used by muscles, the pump, anything that needs energy needs ATP. Na/K pump – blocked by digitalis to allow Na to go into cardiac muscle, so Ca channels open to increase force of contraction (therefore, sometimes you want the pump blocked), and sometimes you want to enhance it.
With no ATP, Na into the cell and it brings H20, which leads to cellular swelling (which is reversible). Therefore, with tissue hypoxia there will be swelling of the cell due to decreased ATP (therefore will get O2 back, and will pump it out – therefore it is REVERSABLE).
In true RBC, anaerobic glycolysis is the main energy source b/c they do not have mitochondria; not normal in other tissues (want to utilize FA’s, TCA, etc)”
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Alright, now in this part of the article, you will be able to access the free Goljan USMLE Step 1 Audio Lectures using our direct links mentioned at the end of this article. We have uploaded a genuine Goljan USMLE Step 1 Audio Lectures to our online file repository so that you can enjoy a blazing-fast and safe downloading experience.
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Please use the direct link mentioned below to download Goljan USMLE Step 1 Audio Lectures free now:
Goljan Rapid Review Pathology |
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Goljan Rapid Review 4th Edition |
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Goljan Audio (5 days) |
Day 1 |
Goljan-High-Yield (Step 1 Remembered Questions) |
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Goljan Pathology Audio Transcripts |
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Goljan Pictures With Notes |
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Goljan Slides |
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Goljan Qbanks |
Goljan Patho Qbank-Immunology.zip |
Goljan Patho Qbank-Histology.zip |
Goljan Patho Qbank-Biostatistics.zip |
Goljan Patho Qbank-Pathology.zip |
Goljan Patho Qbank-Microbiology.zip |
Goljan Step 1 High Yields.apkg (Anki) |
Goljan_High_yield_Pathology_Questions.pdf |
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Like many of you, I listen to Goljan while driving/walking/whatever. Maybe it was just me, but it drove me absolutely insane that it was segmented into different files and not coherent chapters. I was constantly skipping around trying to find the next one to finish the unit. Also, the background noise was super distracting and the audio irregularity would make my sphincter clench every time he yelled.
As such, I’ve spliced the corresponding chapter files together, removed as much of the background noise as my editing software will allow, flattened the audio, and re-uploaded the Goljan audio. Now all of GI can be found in GI, all of nutrition in nutrition, and so on.
Peace n Blessinz.
Edit: Yes, you have to make an account to download the MP3s because it is 3.4GB. Once you make an account, click on the right side where it says VRB MP3 (15 files). Download those and you're done.
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edit again: If the first link isn't working for you, try herehttp://www.mediafire.com/folder/49ei42pw6kpdp/Goljan_Edited